Difference Between Overlap Syndrome And Mixed Connective Tissue Disease

Difference Between Overlap Syndrome And Mixed Connective Tissue Disease
Difference Between Overlap Syndrome And Mixed Connective Tissue Disease

Video: Difference Between Overlap Syndrome And Mixed Connective Tissue Disease

Video: Difference Between Overlap Syndrome And Mixed Connective Tissue Disease
Video: Mixed Connective Tissue Disease mnemonic 2024, Balandis
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The key difference between Overlap Syndrome and Mixed Connective Tissue Disease is that the mixed connective tissue disease is one variety of the overlap syndrome. That is, the overlap syndrome is a special subgroup of connective tissue disorders, characterized by the presence of clinical features of more than one autoimmune rheumatic disease. On the other hand, the characteristic feature of mixed connective tissue disorder is the presence of clinical features corresponding to systemic sclerosis, SLE, rheumatoid arthritis, and polymyositis, along with an increase in the antibodies against ribonuclear proteins (U1 RNP).

Connective tissue disorders are one of the commonest causes of morbidity in the elderly people. Although the incidence and prevalence of these diseases are high among the elderly, they can affect the people of any age group.

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